Surgical Efficacy

For the absolute best in orthopaedic, renal, neurological, and cardiovascular surgical capabilities, MPI Research provides top-notch services to pharmaceutical and biotechnology companies developing new medical treatments. Sponsors frequently attest to the superior research they receive at MPI Research by citing our advanced technologies, excellent facilities, and depth of experience. Sponsors can count on speedy study initiation in a wide range of animal species when they partner with MPI Research.

With a highly skilled professional/technical staff and state-of-the-art equipment, MPI Research offers its Sponsors comprehensive testing services throughout their preclinical device discovery and development process.

Surgical models and capabilities

  • Joint/cartilage
  • Bone fracture/defect repair
  • Spinal fusion and spinal instability/fixation
  • Aminoglycoside nephrotoxicity
  • Renal ischemia-reperfusion injury
  • Glomular filtration rate and renal blood flow evaluations
  • Renal transplantation
  • Goldblatt hypertension
  • Partial nephrectomy for evaluating hemostasis
  • Full thickness excision
  • Split thickness wound created with dermatome
  • Full thickness incision
  • Acute myocardial infarction
  • Congestive heart failure
  • Chronic cardiac and peripheral ischemia
  • Peripheral arterial disease
  • Spinal cord contusion
  • Intrathecal device implantation
  • Epidural device implantation
  • Intracranial device implantation
  • Stereotaxic administration
  • Small/large molecule
  • Autologous cell therapy
  • Allogeneic cell therapy
  • Embryonic cell therapy
  • Gene therapy
  • Proof-of-concept
  • Safety and biodistribution
  • Tumorigenicity
  • Acute chronic toxicity