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VMS Brings Electronic Records to Animal Care

by Dale Cooper, DVM, DACAM

Ensuring quality animal health records has been enhanced with the launch of the Veterinary Management System (VMS), an electronic records tool now in use at MPI Research.

The human health care community has struggled for many years to develop an effective electronic medical records system. Various resources have emerged, especially since passage […]

By | 2014-10-28T14:04:42+00:00 October 6th, 2014|Blog|Comments Off on VMS Brings Electronic Records to Animal Care

Molecular Imaging Yields New Insights in Drug Development

by Scott Haller, MS

The advancement and incorporation of novel technologies into the development of breakthrough medicines is an exciting reality of contemporary science. The application of molecular imaging in drug development is a great example. This evolving discipline is providing new insights into the biological effects of future therapeutics.

Today’s imaging systems allow for non-invasive, in […]

By | 2017-07-04T10:27:40+00:00 June 5th, 2014|Blog|Comments Off on Molecular Imaging Yields New Insights in Drug Development

Clearing Hurdles through New Bioanalytical Testing Tools

by Roger Hayes, PhD

As promising drugs emerge with high-potency, active ingredients, new technological tools to analyze them are emerging.

In my previous blog , I covered some of the unique challenges that these drugs pose to bioanalytical testing. Most of those issues involve eliciting reliable, high-quality data from ever-shrinking sample […]

By | 2017-07-04T10:27:41+00:00 May 21st, 2014|Blog|Comments Off on Clearing Hurdles through New Bioanalytical Testing Tools

Bioanalytical Testing Addresses ‘Potent’ Challenges

by Roger Hayes, PhD

As the call for more effective and targeted medicines grows, an increasing number of drug makers are turning to highly potent, active ingredients. That’s posing a unique set of challenges across the development spectrum. At the preclinical level, CROs are facing them with innovative technologies, processes, and skills.

In bioanalytical testing, keeping pace […]

By | 2017-07-04T10:27:42+00:00 May 13th, 2014|Blog|Comments Off on Bioanalytical Testing Addresses ‘Potent’ Challenges

Dietary Study Unveils New Source for Infant Formula Nutrient

For the health and growth of infants in their first year, nothing beats mother’s milk. But when breast milk isn’t an option, high-quality infant formula is a crucial substitute. Every day, scientists are working on new ways to bring these nutritional formulas closer to Mom’s ideal.

There are many instances in which an infant can’t be […]

By | 2015-05-18T12:20:02+00:00 May 6th, 2014|Blog|Comments Off on Dietary Study Unveils New Source for Infant Formula Nutrient

Measuring Success: Tracking Biodistribution of Stem Cell-derived Cell Therapeutics

Haiyan Ma, PhD
Principal Scientist, Cellular and Molecular Biology

Jia-Hao Xiao, PhD
Director, Oncology and Cell Therapeutics

Measurement is the heartbeat of great science. It’s also a vital and complicated process that must be done extremely well in terms of scientific validity and quality as well as regulatory compliance. This is especially true in the field of developing stem […]

By | 2017-07-04T10:27:49+00:00 April 21st, 2014|Blog|Comments Off on Measuring Success: Tracking Biodistribution of Stem Cell-derived Cell Therapeutics

The Fundamentals of Immunotoxicity Assessment

by Adam Aulbach, DVM, DACVP
Director of Clinical Pathology

Modern R&D shines best in the shadow of failure. Put another way, the ability to weed out doomed drug candidates early means resources are focused on the most promising compounds. Assessing immunotoxicity in preclinical safety studies is key to determine early on a drug’s future.

Immunotoxicity is a measure […]

By | 2014-10-27T15:49:35+00:00 March 24th, 2014|Blog|Comments Off on The Fundamentals of Immunotoxicity Assessment

The Cyclotron Advantage

by Scott Haller, MS
Director of the Translational Imaging Center

Incorporating molecular imaging into development efforts will allow investigators to visualize, characterize, and quantify biological, physiological, and chemical processes at the molecular and cellular levels in vivo. Molecular imaging platforms such as Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) detect emission products of […]

By | 2014-10-03T17:19:07+00:00 March 7th, 2014|Blog|Comments Off on The Cyclotron Advantage

Evaluating Vaccines: From Hypothesis through Preclinical Study

by Stephene Rose
Senior Study Director, Drug Safety

The science of immunogenicity began similarly to how today’s medical breakthroughs occur: with a carefully reasoned hypothesis.

In 1796, English physician Edward Jenner noticed that milkmaids who contracted cowpox, a relatively non-threatening skin disease, were usually immune to the much deadlier smallpox disease. Thinking that inoculation with pus from cowpox […]

By | 2017-07-04T10:27:59+00:00 February 5th, 2014|Blog|Comments Off on Evaluating Vaccines: From Hypothesis through Preclinical Study

New Vaccines, New Applications Take to Disease Battlefield

by Stephene Rose
Senior Study Director, Drug Safety

You and I probably share a common childhood memory: a white-coated doctor whose compassionate manner seemed at odds with the sharp hypodermic needle he or she jabbed into your arm. But the fact is, that momentary painful poke might have saved your life.

Few […]

By | 2017-07-04T10:28:01+00:00 January 20th, 2014|Blog|Comments Off on New Vaccines, New Applications Take to Disease Battlefield