MPI Research

/MPI Research

About MPI Research

MPI Research, with global headquarters in Mattawan, Mich., provides safety evaluation, discovery, bioanalytical and analytical services to the biopharmaceutical, medical device, animal health, and chemical industries. The company offers comprehensive imaging solutions including preclinical imaging, radiochemistry, and data analysis. Scientific knowledge and experience, responsiveness, integrity, trust, teamwork, and dedication to strong and enduring Sponsor relationships are the defining attributes that characterize MPI Research as a high-performance, high-quality organization that is committed to bringing safer and more effective products to the world.

Finding the Right DMPK Partner

by Ric Slauter, PhD, DABT

The 20th century saw amazing, life-saving discoveries in medical research. That innovative spirit remains strong in the new century, even as it advances into more complex areas of study, more complicated diseases, and more rigorous standards. Finding a partner who expertly balances those dynamics is key to advancing drug development.

Today’s medical […]

By | 2017-07-04T10:27:33+00:00 December 17th, 2014|Blog|Comments Off on Finding the Right DMPK Partner

The Strongest Rope: Early PK-PD Modeling

by Ric Slauter, PhD, DABT

The strongest rope is one made of multiple cords woven tightly together. Likewise, applying the closely associated tools of pharmacokinetics and pharmacodynamics early in drug development can lift the best candidates above the also-rans.

While pharmacokinetics (PK) and pharmacodynamics (PD) have a strong relationship, they’ve been approached separately in the past: PK […]

By | 2017-07-04T10:27:34+00:00 December 17th, 2014|Blog|Comments Off on The Strongest Rope: Early PK-PD Modeling

Tracking Biodistribution with Molecular Imaging

by Scott Haller, MS

Medical advancements must bear scrutiny—including the presumed unlimited promise of stem cell-based therapies. Fortunately, that scrutiny is possible through many assays, including non-invasive imaging methods that provide crucial data on biodistribution of these potential new treatments.

Tracking the distribution and fate of implanted or transplanted stem cells is important to understanding where in […]

By | 2014-12-12T17:20:37+00:00 December 12th, 2014|Blog|Comments Off on Tracking Biodistribution with Molecular Imaging

Lessons Learned in Juvenile Toxicity Testing

by Ali Said Faqi

One area where this is especially true is juvenile toxicity testing. We know there are profound differences between adults and children in drug disposition and effect; yet most drugs prescribed to children have not been adequately studied in the young.

Fortunately, the pharmaceutical industry and regulatory agencies are starting to address this issue. […]

By | 2014-11-26T17:15:36+00:00 November 26th, 2014|Blog|Comments Off on Lessons Learned in Juvenile Toxicity Testing

Stem Cell-Derived RPE Cells Sharpen View of Retinal Disease

by Thomas Vihtelic, DVM, PhD
Director of Experimental Therapeutics, MPI Research

Advancing stem cell research is a rewarding part of our work at MPI Research. We also follow related scientific achievements, as these can enhance our own understanding and expertise. For example, two recent studies involving stem cells and retinal disease are providing valuable insights. […]

By | 2017-07-04T10:27:36+00:00 November 19th, 2014|Blog|Comments Off on Stem Cell-Derived RPE Cells Sharpen View of Retinal Disease