MPI Research

/MPI Research

About MPI Research

MPI Research, with global headquarters in Mattawan, Mich., provides safety evaluation, discovery, bioanalytical and analytical services to the biopharmaceutical, medical device, animal health, and chemical industries. The company offers comprehensive imaging solutions including preclinical imaging, radiochemistry, and data analysis. Scientific knowledge and experience, responsiveness, integrity, trust, teamwork, and dedication to strong and enduring Sponsor relationships are the defining attributes that characterize MPI Research as a high-performance, high-quality organization that is committed to bringing safer and more effective products to the world.

Bioanalysis Zone WRIB Panel Discussion – Part 1: Outsourcing

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By | 2017-07-04T10:26:19+00:00 July 12th, 2016|Video|Comments Off on Bioanalysis Zone WRIB Panel Discussion – Part 1: Outsourcing

Lessons Learned in Preparing Nonclinical Programs Part I:

Test Article Considerations

Effects: Sharing as much information as you can with your contract research organization (CRO) about your test article and its known or potential effects is a critical component of the study design process. Have in-depth discussions about the structure, class, intended use, mechanism of action, previous findings, and anything else that may affect […]

By | 2017-07-04T10:26:21+00:00 July 10th, 2016|Lessons Learned: Nonclinical Programs|Comments Off on Lessons Learned in Preparing Nonclinical Programs Part I:

Lessons Learned in Preparing Nonclinical Programs Part II:

Species Selection

The basic question that helps to address this is “what is your test article type?”.  For small molecules, invariably there will be two species needed; a rodent and a non-rodent, while for a biopharmaceutical it could be either one species or two species. While there is public pressure to minimize the use of species […]

By | 2017-07-04T10:26:25+00:00 July 9th, 2016|Homepage Featured, Lessons Learned: Nonclinical Programs|Comments Off on Lessons Learned in Preparing Nonclinical Programs Part II:

Lessons Learned in Preparing Nonclinical Programs Part III:

Analytical/Bioanalytical Methods

Validated analytical/bioanalytical methods will be required to determine the amount of drug administered to the animals, the amount of circulating drug in the serum/plasma, and the presence of antibodies against the drug (applies only to biopharmaceuticals) in the serum.  Depending on your project, you may also need analytical methods for other matrices such as […]

By | 2017-07-04T10:26:27+00:00 July 8th, 2016|Lessons Learned: Nonclinical Programs|Comments Off on Lessons Learned in Preparing Nonclinical Programs Part III:

Lessons Learned in Preparing Nonclinical Programs Part IV:

Administrative Issues

Contracts: When outsourcing your work to a CRO, you need to ensure that you are protected from a legal standpoint.  There are two basic contracts that you will need.  The first is a confidentiality contract (also called a CDA or NDA), which will protect any conversations you have with the CRO as being privileged […]

By | 2017-07-04T10:26:32+00:00 July 7th, 2016|Lessons Learned: Nonclinical Programs|Comments Off on Lessons Learned in Preparing Nonclinical Programs Part IV:

MPI Research Adds Two to Pathology Team; Extends Position as Industry Leader

Mattawan, Mich. – MPI Research affirmed its position as a global leader in pathology capabilities today, announcing the addition of industry experts Justin Vidal, DVM, PhD, DACVP, and Joshua Decker, DVM, DACVP.

Dr. Vidal, internationally recognized as one of the world’s leading experts within the reproductive toxicologic pathology field, joins MPI Research as Senior Principal Pathologist.

“The […]

By | 2017-07-04T10:26:35+00:00 May 31st, 2016|News|Comments Off on MPI Research Adds Two to Pathology Team; Extends Position as Industry Leader

MPI Research Appoints Robert H. DeWit as President

Mattawan, Michigan – MPI Research today announced that its board of directors has named Robert H. DeWit, PhD, DABT, as president, effective immediately. DeWit will assume responsibility for the day-to-day operations of the Company.

“The addition of Rob to our executive team will be invaluable as MPI Research continues to grow in the marketplace,” said Lisa Yoder, […]

By | 2017-07-04T10:26:36+00:00 May 3rd, 2016|News|Comments Off on MPI Research Appoints Robert H. DeWit as President

Hernia Treatment Evaluation

With more than one million hernia repairs performed each year in the U.S., a hernia is an all-too common condition for many.  A hernia occurs when an organ pushes through an opening in the muscle or tissue that holds it in place. They are most common in the abdomen, when intestines break through a weakened […]

By | 2017-07-04T10:26:40+00:00 April 29th, 2016|Blog, Homepage Featured|Comments Off on Hernia Treatment Evaluation