MPI Research

Home/MPI Research

About MPI Research

MPI Research, with global headquarters in Mattawan, Mich., provides safety evaluation, discovery, bioanalytical and analytical services to the biopharmaceutical, medical device, animal health, and chemical industries. The company offers comprehensive imaging solutions including preclinical imaging, radiochemistry, and data analysis. Scientific knowledge and experience, responsiveness, integrity, trust, teamwork, and dedication to strong and enduring Sponsor relationships are the defining attributes that characterize MPI Research as a high-performance, high-quality organization that is committed to bringing safer and more effective products to the world.

Risks and Effects of Ototoxic Medications

Bringing a new drug to market is not a simple task and due to regulations and high costs associated with the process, drug developers often pass on conducting optional testing. Ototoxicity is one example of a frequently forgone test as it’s not required by the FDA for medications that are not administered into the ear. […]

By | 2017-08-16T13:07:50+00:00 August 16th, 2017|Blog|Comments Off on Risks and Effects of Ototoxic Medications

Key Considerations in Ototoxicity Study Design

For drugs administered into the middle ear, those expected to come in contact with the middle or inner ear tissues, or drugs in a class of risk for ototoxicity, auditory safety evaluations are recommended. These assessments require a highly specialized set of tests to obtain the necessary data in order to identify the ototoxicity of […]

By | 2017-07-04T10:26:10+00:00 May 24th, 2017|Blog|Comments Off on Key Considerations in Ototoxicity Study Design

The Benefits of In-house Ototoxicity Work

Certain medications can damage the ear, resulting in hearing loss, ringing in the ears, hyperacusis, or balance disorders. Thus, many drugs should be tested for auditory safety prior to going to market.  While some contract research organizations (CROs) offer ototoxicity services, portions of the studies are often outsourced to other specialized shops or academic labs. […]

By | 2017-07-04T10:26:11+00:00 April 28th, 2017|Blog|Comments Off on The Benefits of In-house Ototoxicity Work

MPI Research Appoints Vice President of Operations

Mattawan, Mich. – MPI Research today announced it has named Susan L. Buckham, MS, as its new Vice President of Operations. In this role, Susan will be responsible for the strategic leadership and overall direction of operational activities for all functional areas involved with the coordination and execution of in vivo studies. In addition, she […]

By | 2017-07-04T10:26:12+00:00 November 29th, 2016|News|Comments Off on MPI Research Appoints Vice President of Operations

MPI Research Offers Validated SEND Capabilities

Mattawan, Mich. – MPI Research announced it has completed the validation of its Instem submit™ software suite, allowing for the creation of consistent, accurate, and high quality datasets compliant with the Standard for Exchange of Nonclinical Data (SEND).

Initially powered by the FDA’s Critical Path Initiative to more efficiently bring medical breakthroughs to market, SEND supports […]

By | 2016-10-20T16:43:42+00:00 October 20th, 2016|News|Comments Off on MPI Research Offers Validated SEND Capabilities

Optimizing Safety Pharmacology Programs to Promote Efficiency and Animal Welfare

The primary objective of safety pharmacology studies is to identify potential adverse functional effects of a compound on the central nervous, respiratory, or cardiovascular systems.

Like many areas of drug development, safety pharmacology is a rapidly progressing industry segment. The technologies and tools available to conduct these studies are evolving and expanding regularly. A critical—and quickly […]

By | 2017-07-04T10:26:13+00:00 October 7th, 2016|Blog|Comments Off on Optimizing Safety Pharmacology Programs to Promote Efficiency and Animal Welfare