MPI Research

/MPI Research

About MPI Research

MPI Research, with global headquarters in Mattawan, Mich., provides safety evaluation, discovery, bioanalytical and analytical services to the biopharmaceutical, medical device, animal health, and chemical industries. The company offers comprehensive imaging solutions including preclinical imaging, radiochemistry, and data analysis. Scientific knowledge and experience, responsiveness, integrity, trust, teamwork, and dedication to strong and enduring Sponsor relationships are the defining attributes that characterize MPI Research as a high-performance, high-quality organization that is committed to bringing safer and more effective products to the world.

Novel Disease Models for Choroidal Neovascularization Studies

Choroidal neovascularization (CNV) involves the development of new blood vessels that originate from the choroidal layer of the eye and invade the outer retina. CNV is the hallmark lesion of wet macular degeneration, a more advanced type of age-related macular degeneration (AMD) responsible for severe vision loss. Developing effective new treatments for CNV requires accurate […]

By | 2017-09-19T15:38:40+00:00 September 19th, 2017|Blog|Comments Off on Novel Disease Models for Choroidal Neovascularization Studies

Risks and Effects of Ototoxic Medications

Bringing a new drug to market is not a simple task and due to regulations and high costs associated with the process, drug developers often pass on conducting optional testing. Ototoxicity is one example of a frequently forgone test as it’s not required by the FDA for medications that are not administered into the ear. […]

By | 2017-08-16T13:07:50+00:00 August 16th, 2017|Blog|Comments Off on Risks and Effects of Ototoxic Medications

Key Considerations in Ototoxicity Study Design

For drugs administered into the middle ear, those expected to come in contact with the middle or inner ear tissues, or drugs in a class of risk for ototoxicity, auditory safety evaluations are recommended. These assessments require a highly specialized set of tests to obtain the necessary data in order to identify the ototoxicity of […]

By | 2017-07-04T10:26:10+00:00 May 24th, 2017|Blog|Comments Off on Key Considerations in Ototoxicity Study Design

The Benefits of In-house Ototoxicity Work

Certain medications can damage the ear, resulting in hearing loss, ringing in the ears, hyperacusis, or balance disorders. Thus, many drugs should be tested for auditory safety prior to going to market.  While some contract research organizations (CROs) offer ototoxicity services, portions of the studies are often outsourced to other specialized shops or academic labs. […]

By | 2017-07-04T10:26:11+00:00 April 28th, 2017|Blog|Comments Off on The Benefits of In-house Ototoxicity Work