MPI Research is pleased announce that Jill Wasielewski, Ph.D., a member of our Safety Pharmacology Team, will be presenting the following poster entitled, “Development and Validation of a Canine Functional Observational Battery (FOB) for use in Toxicity Studies,” poster number 1286 on Wednesday, March 20, 2002 at the Society of Toxicology Meeting in Nashville, Tennessee at 8:30 –11:30 am. The need for, and utility of a robust and yet sensitive canine screening method for detecting and providing initial characterization of neurotoxic and neurofunctional effects is clear. In response to customer demand for such a model, we have recently developed and validated a canine neurobehavioral test battery that has demonstrated sensitivity to neurofunctional effects of a variety of pharmacological positive control articles.

Theodore J. Baird, Ph.D., Study Director for Neurosciences stated, “It has become evident that for a variety of reasons, rodent models may not always be practical to meet our sponsors’ specific needs for neurobehavioral testing. As always, our sponsors’ needs drive our business decisions, and we felt it imperative to develop and validate a canine neurobehavioral test battery that will meet regulatory guidelines for nervous system safety evaluation. Dr. Wasielewski’s involvement has been a critical factor in driving this validation project, and we are proud to have her as a member of our team.”

MPI Research exists to provide non-clinical research that meets the requirements of pharmaceutical, animal health and chemical companies as well as governmental agencies, as they develop products for a healthier world. MPI employees specialize in a wide variety of scientific disciplines including toxicology, pharmacology, metabolism, pathology, clinical pathology, reproductive and developmental biology, veterinary science, neuroscience, analytical chemistry, computer science, regulatory science, and statistics.

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